Advanced Approaches/ Targeted Technology Solution
Element
Key Institutional Partners
  • Consider antithrombotic catheters in patients at high risk of DVT
    • Endexo PICCs (e.g., BioFlo)
Providers, IR, Vascular Team, Hospital Leadership/Nursing Leadership
  • Reversed taper catheters have conflicting data – the HMS Coordinating center does not recommend using these as a strategy to reduce rates of PICC DVT in view of the lack of evidence for these devices
Providers, IR, Vascular Team, Hospital Leadership/Nursing Leadership
Articles/References
​Ullman AJ, et al. Antithrombogenic peripherally inserted central catheters:  Overview of efficacy and safety. Taylor & Francis Online 2018
  • A review of published and unpublished laboratory and clinical studies was performed to evaluate the effectiveness, efficiency, and safety of antithrombogenic PICCs. Early studies show promise, however furthers trials are needed to establish results.
​Ullman AJ, et al. Do antimicrobial and antithrombogenic peripherally inserted central catheter (PICC) materials prevent catheter complications? An analysis of 42,562 hospitalized medical patients. Infect Control Hosp Epidemiol. 2021;1-8. doi:10.1017/ice.2021.141
  • A study of 52 hospitals found that antimicrobial and antithrombogenic PICCs were not associated with a reduction in major catheter complications. Guidance aimed at informing use of these devices, balancing benefits against cost, appear necessary.
Validation Survey
DVT Step 4 Validation - Advanced Approaches/Targeted Technology Solutions.
  • This document includes all of the validation questions associated with this content area to help with collaboration on responses for your hospital. Responses to the validation questions should be entered in to the linked document and recorded to monitor progress.